MACSE Programs

Aligning or merging two alignments A key step in MACSE optimization procedure is aligning two multiple sequence alignments (also called profiles), each of which containing a subset of the input sequences. This procedure is the same as 2-cut strategy used in muscle and in many other multiple sequence alignment software. If you have already two … Lire la suite

Sequence alignment The MACSE subprogram alignSequences aligns protein-coding sequences at the nucleotide level while scoring the considered nucleotide alignments based on their amino acid translation. It thus favours nucleotide gap stretches that are multiple of three but also considers those inducing frameshifts, when they allow to recover the underlying codon structure. MACSE therefore produces alignments … Lire la suite